Cat’s claw is an ancient plant extract used for centuries by Peruvian tribes for immune support
In the early 2000’s, while a Research Associate Professor of Pathology at University of Washington, Dr. Alan Snow and his world-class research teams went on a screening expedition after they developed a proprietary assay to identify the most potent inhibitors/reducers of brain plaques. They screened many dietary supplements that were available in the marketplace for human consumption at the time, looking for a natural inhibitor and reducer of brain plaques (that accumulate in the normal aging brain).
Brain plaques, and then later tangles, were the two main culprits identified to be the actual cause of normal memory loss as one gets older. The Snow neuroscience team, while at the University of Washington, identified an ancient plant extract known as Uncaria tomentosa (Cat’s claw) that was used for centuries by the Peruvian tribes for immune support and enhancement (1-2) The Cat’s claw ingredient was found to be a potent inhibitor and disrupter of brain plaques (that consisted of a protein called “beta-amyloid protein”)(3-5). The Snow research teams spent years screening different sources to identify the specific, proprietary Cat’s claw that produces the most potent activity against brain plaques: PTI-00703® Cat’s claw (4-6).
Dr. Snow and his research teams have now identified the specific and newly discovered polyphenol ingredients within PTI-00703® Cat’s claw that are responsible for the potent activity that they first identified. These ingredients and the exact mechanism of action of how this amazing plant extract works to reduce brain plaque load and improve memory was recently published in a landmark 108-page paper by Snow et al on Feb 6, 2019 in Nature - Scientific Reports by Snow et al (7).